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Are you the one who helps prevent Alzheimer’s?

Do something unforgettable today. Take part in research to help prevent Alzheimer’s.

We are looking for individuals, aged 60-75 years, who have not been diagnosed with any memory impairment, but have a specific form of a gene that can increase the risk of developing Alzheimer’s. This website is intended for residents of Canada. If you are based outside of Canada, please choose your country at the top of the page.

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About the
Generation Program.

The Generation Program is made up of two clinical trials: Generation Study 1 and Generation Study 2. Each trial will last for 5 – 8 years and will be investigating treatment that may be able to prevent the onset of Alzheimer’s disease. We’ll have many study sites across Canada - find the one closest to you.

To test our investigational treatment, we’re asking people like you to help. We’re not looking for people with Alzheimer’s, but rather those with a specific form of a gene that can increase the risk of developing the disease.

Not everyone will have this. That’s why we’ll need to get you to take a quick cheek swab test before you can be enrolled, just to see if you’re eligible for the trial.

Only with your help will the trial have the chance to succeed.

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The key facts:

  • The clinical trial will last 5 - 8 years
  • You’ll receive an investigational treatment or a placebo, at no cost
  • Regular study visits at study doctor office (8 in the first year, 4 visits a year thereafter)
  • Reasonable travel costs will be reimbursed
  • Participation is voluntary, you can leave at any time

How it all works.

Step 1

Eligibility

To qualify you must:

  • Be 60-75 years of age
  • Have not been diagnosed with any memory impairment
  • Have a study partner

We’ll have study sites across Canada - find your nearest one.

Step 2

Genetic testing

To proceed, we need to know whether your genetics show that you have an increased risk of Alzheimer’s. This requires a quick cheek swab test at your local study site.

Step 3

Do something amazing

If you’re eligible for the Generation Program and choose to take part, you’ll be one of the few that can join the fight to prevent Alzheimer’s.

Do something amazing.

If you’re eligible for the Generation Program and choose to take part, you could be one of the few that can join the fight to prevent Alzheimer’s. You will need to attend regular visits to your local study site throughout the study.

We need to ask you a few quick questions to check your eligibility for the Generation Program.


Eligibility

  • I am 60 – 75 years of age
  • I have not been diagnosed with Alzheimer’s disease or any other condition that affects my memory, thinking or judgement
  • I’m willing to consider attending regular visits to my nearest study site over a 5-8 year period
  • I’m willing to complete a cheek swab test at my first appointment to test for my APOE4 genotype
  • I have not been diagnosed with any of the following diseases or conditions: Huntington’s disease, Parkinson’s disease, Lyme disease, Schizophrenia, Bipolar disorder, Active seizure disorder, multiple traumatic brain injuries, congestive heart failure, active hepatitis, kidney impairment or liver impairment
  • I do not currently have an alcohol or drug dependency
  • I have not been diagnosed with cancer, excluding localized basal or squamous cell carcinoma, in the past five years
  • I have someone who is willing to be my study partner in this study. (Click here for more information about study partners.)
  • I agree to contact a local study site near me to discuss the next steps of this study

If you have answered YES to all statements listed above, you may be eligible for the Generation Program. Please contact the Generation study site closest to where you live. Choose your preferred study location from the list below.

If you have not answered YES to all statements above, unfortunately you are not eligible to take part in the Generation Program. However, not all Alzheimer’s clinical trials have the same requirements. If you’re still interested in helping to beat Alzheimer’s, you can check out the Alzheimer Society of Canada website at www.alzheimer.ca

Thank you for your interest in research for Alzheimer's.


Any questions?

If you would like to find out more information about the Generation Program you can contact the Generation study site closest to where you live.


Choose your preferred study location from the list below.

Dr. Paul Latimer

Kelowna, BC

250-862-8141


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Dr. Mark Allan

Kentville, NS

902-679-0536


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Dr. Ron Wojcik

Halifax, NS

902-431-4433


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Dr. Michael Borrie

London, ON

519-646-6100 ext. 42711


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Dr. Sharon Cohen

Toronto, ON

416-386-9761 ext 347


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Dr. Mario Masellis

Toronto, ON

416-480-6100 ext 1620


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Dr. Giovanni Marotta

Toronto, ON

416-663-6879


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Dr. Richard Bergeron

Gatineau, QC

819-510-1000


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Dr. Louis Verret

Québec, QC

418-649-0252 ext. 63711


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Dr. Simon Ducharme

Montreal, QC

514-398-2733


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Dr. Richard Bergeron

Ottawa, ON

613-702-1000


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Visit us again soon to see new available sites! You can also speak to your doctor about your interest in Alzheimer’s disease research in your area.

The people behind the Generation Program.

The Generation Program is a collaboration between a group of leading research organizations. Many of the people involved have been touched in some way by Alzheimer’s.

Novartis

A global healthcare company that provides solutions to address the evolving needs of patients worldwide.

Amgen

One of the world’s leading biotechnology companies, deeply rooted in science and innovation to transform new ideas and discoveries into medicines for patients with serious illnesses.

A world leading non-profit organization in Alzheimer's research and care, dedicated to preventing the disease as soon as possible.